141 – Developing More Sensitive, Comprehensive, and Efficient Anti-Doping Analysis Methods – Michaël Polet, PhD
Dr. Michaël Polet is a faculty member in the Department of Diagnostic Sciences and Head of the IRMS (isotope ratio mass spectrometry) Department in the Doping Control Laboratory (DoCoLab) at Ghent University in Belgium. In this episode, he discusses PCC-funded research projects he has led to improve anti-doping analyses by developing new gas chromatography-chemical ionization-tandem mass spectrometry (GC-CI-MS/MS) methods, as well as a novel chromatography high-resolution acquisition screening method. Michaël also discusses recent work using high-temperature liquid chromatography-isotope ratio mass spectrometry methods that will help improve steroid detection and potentially lead to future high-throughput analysis methods.
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140 – Conducting Research to Improve Doping Tests for Steroids and Other Substances – Lena Ekström, PhD
Dr. Lena Ekström is a Hospital Chemist at Karolinska University Hospital and an Adjunct Professor of Pharmacology in the Department of Laboratory Medicine at the Karolinska Institute, where she specializes in Doping Research. In this interview, we discuss her career and some of the research she has conducted examining various factors that can influence anti-doping test results including interactions with other substances, genetics, hormone cycles, biological variability, and micro-dosing.