140 – Conducting Research to Improve Doping Tests for Steroids and Other Substances – Lena Ekström, PhD
Dr. Lena Ekström is a Hospital Chemist at Karolinska University Hospital and an Adjunct Professor of Pharmacology in the Department of Laboratory Medicine at the Karolinska Institute, where she specializes in Doping Research. In this interview, we discuss her career and some of the research she has conducted examining various factors that can influence anti-doping test results including interactions with other substances, genetics, hormone cycles, biological variability, and micro-dosing.
Support This Podcast
Interested in sponsoring the Anti-Doping Podcast or have a guest recommendation?
139 – Applying Targeted Proteomics Approaches in Anti-Doping Research – Christoph Borchers, PhD
Dr. Christoph Borchers is a Full Member in the McGill Centre for Translational Research in Cancer, Senior Investigator at the Lady Davis Institute for Medical Research, Director of the Segal Cancer Proteomics Centre, and Professor in the Department of Oncology at McGill University. In this episode, Christoph discusses his research in the area of proteomics and important applications of his work in anti-doping, including a PCC-funded research project examining quantitative proteomics longitudinally in blood to screen for blood doping. He also shares future directions for this line of research and his perspectives on important areas of opportunity in anti-doping science.
138 – How the Team USA Athletes’ Commission is Empowering Athletes and the Athlete Voice – Elizabeth Ramsey
Elizabeth Ramsey, Executive Director of the Team USA Athletes’ Commission (formerly the USOPC Athletes’ Advisory Council) joins this episode to discuss how the Commission is working to empower Team USA athletes to inspire and drive positive change. She shares how the Commission is organized, what it can do to help athletes, and how it’s critical for athletes to be engaged in the governance of sport to ensure their views are taken into account in making decisions that will impact them. We also specifically discuss important issues related to anti-doping that the Team USA Athletes’ Commision has been working on, the impacts of the recent 2024 Olympic and Paralympic Games, and more.
137 – Investigating the Science Behind Doping Motivations and Psychosocial Predictors of Doping – Nikos Ntoumanis, PhD
Dr. Nikos Ntoumanis is Professor and Director in the Danish Centre for Motivation and Behaviour Science in the Department of Sports Science and Clinical Biomechanics at the University of Southern Denmark. In this episode, Nikos discusses important research he has been conducting on factors that are relevant for doping intentions and doping behaviors, including environmental factors like the style of coaching an athlete receives, as well as athletes’ personal motivations and moral attitudes. He also discusses a recent a PCC-funded meta-analysis that provides an updated look at the evidence on personal and psychosocial predictors of doping use in physical activity settings.
136 – Anti-Doping Research and Innovation at the UK’s Drug Control Center – Kim Wolff, PhD
Professor Kim Wolff is Director of King’s Forensics and head of the Drug Control Centre, which is the only WADA accredited laboratory for sports testing in the United Kingdom. She is also Director of the London Athlete Passport Management Unit (APMU), and she was named a Member of the Most Excellent Order of the British Empire (MBE) for her services to road safety. Kim discusses her career and her work leading the WADA-Accredited Doping Control Centre and their APMU. She shares insights on the lab’s history, how they have incorporated the Endocrine Module of the Athlete Passport into their operations, and areas of opportunity in anti-doping and forensic toxicology research. Kim also touches on ongoing research projects focused on detecting the administration of naturally occurring steroids, identifying and measuring longer-term steroid metabolites, detecting steroids and other substances using dried blood spots, and more.
135 – The Critical Role of Intelligence and Investigations in Sport and Anti-Doping – Nick Raudenski
Nick Raudenski is an independent Consultant and also Head of the Fight against Technological Fraud at the International Cyclist Union (UCI). Prior to his current positions, Nick’s career spanned work in criminal investigations for the U.S. Government and sport integrity roles for the Federation Internationale de Football Association (FIFA), the Union of European Football Associations (UEFA), and the International Testing Agency (ITA). In this episode, he shares more about his career and his work in intelligence and investigation (I&I) across multiple different sport organizations, some of the changes and challenges he has seen in the sports landscape over the years, and potential directions for the future.
134 – Fostering International Cooperation and Collaboration with the Anti-Doping Convention – Julien Attuil-Kayser and Liene Kozlovska, MD
Adopted in 1989, the Council of Europe’s Anti-Doping Convention unites stakeholders from member states and provides a framework for working together to protect clean sport and fair play. This episode features two guests from the Council of Europe, Julien Attuil-Kayser and Dr. Liene Kozlovska. Julien recently served as the Head of the Anti-doping Unit, and Liene is the Anti-doping Senior Project Officer. In this episode, they discuss the history of the Council of Europe, the important role the organization plays in the clean sport movement, how the Anti-Doping Convention came to be, how it works today, and more.
133 – Austria’s Doping Control Laboratory Advances Anti-Doping Research and Clean Sport – Günter Gmeiner, PhD
Dr. Günter Gmeiner is Head of the World Anti-Doping Agency (WADA)-accredited Seibersdorf Doping Control Laboratory in Austria, as well as the Forensic Analytics Laboratory there. In this interview, Günter describes his scientific background, the history of the Austrian Doping Control Laboratory, how the lab has grown and evolved since it was established, their PCC-funded research developing important reference materials, current research projects in the lab, the impacts of the 2024 Olympic and Paralympic Games on the lab’s activities, and more.
132 – Building a Global Sports Law Website, Knowledge Hub, and Community – Sean Cottrell
Sean Cottrell is CEO and Co-founder of LawInSport, the world’s leading sports law website, knowledge hub, and global community of more than 30,000 members. In this episode, he shares the story of how LawInSport came to be, how it has grown into the organization that it is today, and what he envisions for the future. We discuss some of the resources they provide athletes, lawyers, and other key stakeholders in the community. Sean also shares his perspectives on changes, challenges, and the importance of partnerships in sport and anti-doping.
131 – Updates and Ongoing Research for the Athlete Biological Passport – Drs. Reid Aikin and Norbert Baume
Dr. Reid Aikin is the Associate Director of the Athlete Biological Passport (ABP), and Dr. Norbert Baume is Senior Manager of the ABP at the World Anti-Doping Agency (WADA). In this episode, they discuss recent updates to the ABP, including the addition of new biomarkers to the Steroidal Module and the creation of the new Endocrine Module. They also share common misconceptions about the ABP and highlight ongoing research that aims to further enhance the ABP and how it can be used to help protect clean sport.
130 – Providing Evidence-Based Information About Dietary Supplements – Andrea Lindsey
Andrea Lindsey is Director of Operation Supplement Safety, the Department of Defense program of record for dietary supplements, a Program of the Consortium for Health and Military Performance of Uniformed Services University. She is also an Assistant Professor at the Uniformed Services University. In this episode, Andrea discusses important issues surrounding dietary supplements, how Operation Supplement Safety got started, and how it is protecting the health and safety of service members today. She also discusses important partnerships and the recent Performance-Enhancing Substances Summit, a collaborative event centered around anti-doping in sport and in the military.
129 – The French Anti-Doping Agency’s Preparations for the 2024 Olympic and Paralympic Games – Francesca Rossi, PhD
Dr. Francesca Rossi is Testing Director at the French Anti-Doping Agency (AFLD) where she also manages international partnerships and serves as a science coordinator. She joined us in this interview to talk about her career and her work at AFLD, including preparations for the 2024 Olympic and Paralympic Games in Paris. Listen to this episode to get a behind-the-scenes look at the important considerations and work done by national anti-doping organizations ahead of a large event like the 2024 Games.
128 – Elite Distance Runner Contributing to Clean Sport Through Research and Advocacy – Andrew Heyes, PhD
Dr. Andrew Heyes is a Postdoctoral Research Fellow at Leeds Beckett University. He is also working on a research project at the University of Birmingham, and he is an elite athlete in the marathon and ultramarathon competing for Great Britain, a member of the World Anti-Doping Agency’s Social Science Research Expert Advisory Group, a Member of the UK Anti-Doping Athlete Commission, and former Chair of the UK Athletics Athletes’ Commission. In this episode, we discuss multiple anti-doping and sport integrity social science research projects that Andrew is working on, as well as his athletic career, and his dedication to anti-doping advocacy.
127 – Advancing Anti-Doping Research and Implementing Dried Blood Spot Testing – Jakob Mørkeberg, PhD
Dr. Jakob Mørkeberg is Senior Science Manager at Anti Doping Denmark. In this episode, he discusses research and development efforts to advance dried blood spot (DBS) testing, how they have implemented DBS methods for drug testing in elite sport and fitness centers in Denmark, and some of the positive cases and athlete sanctions from DBS tests. Jakob also covers their ongoing research to better understand the scope of doping and doping substances in Denmark, important collaborations and partnerships that are helping them advance clean sport, and more.
126 – Studying the Experiences and Perspectives of Clean and Sanctioned Athletes – Cornelia Blank, PhD, and David Müller, PhD
In this episode, Dr. Cornelia Blank and Dr. David Müller discuss a newly launched collaborative research project they are leading that is examining the experiences and perspectives of sanctioned athletes as well as clean athletes. The project is called Transforming Athletes’ Life Experiences after Doping into Education Resources and Policy Recommendations (TALE), and you can learn more at https://athletes-tale.eu/. Cornelia is Professor and deputy head of the Institute for Sports Medicine, Alpine Medicine and Health Tourism at the University for Health Sciences and Health Tech in Hall in Tirol, Austria. David is Head of Information and Education at the National Anti-Doping Agency Austria (NADA Austria). He is also head of the Medical Department and is the Quality Manager at NADA Austria.
125 – Combatting Doping in Norwegian Sport and Among Youth in Norway – Anders Solheim
Anders Solheim is CEO of Anti-Doping Norway, and he was recently elected as the Chair of the Board of the Institute of National Anti-Doping Organisations (iNADO). In this episode, Anders talks more about his career, his work as part of iNADO, landmark accomplishments for clean sport in Norway over the years, how the organization supports anti-doping research, current challenges in anti-doping, Anti-Doping Norway’s goals for the future, and more.
124 – Health and Clean Sport Risks of Supplements, Research Chemicals, and Biologics – Amy Eichner, PhD
Dr. Amy Eichner is the Special Advisor on Drugs and Supplements at the U.S. Anti-Doping Agency (USADA). In this episode, she discusses risks and considerations for athletes who are thinking about taking dietary supplements, and work that USADA is doing to help reduce supplement-related risks for athletes. Dr. Eichner also covers research chemicals, some of the novel substances that are relevant in the context of clean sport, the anti-doping implications of the growing field of biologics, and more.
123 – Leading Routine Work, Research, and Development in LA’s Anti-Doping Lab – Brian Ahrens
Brian Ahrens is Director of the UCLA Olympic Analytical Laboratory in Los Angeles. In this episode Brian shares insights from more than three decades working in a WADA-accredited anti-doping laboratory, details on their daily operations, research and development efforts they are working on now, areas of opportunity in anti-doping research, and their preparations for the 2028 Olympic and Paralympic Games which will be held in Los Angeles.
122 – Protecting Clean Sport and Public Health in Denmark – Kim Ravn
Kim Højgaard Ravn is Chief Executive Officer of Anti Doping Denmark, and he has worked for the organization for over ten years, serving in a variety of roles to advance clean sport. In our interview, Kim talks about his career, how the anti-doping landscape has evolved over the past decade, and the organization’s commitment to clean sport and supporting anti-doping science. Kim discusses the work they are doing at Anti-Doping Denmark currently, including anti-doping efforts in organized sports and also in gyms and fitness centers across the country.
121 – Directing the Brazilian Doping Control Lab and Advancing Anti-Doping Research – Henrique Pereira, PhD
Dr. Henrique Marcelo Gualberto Pereira is Director of the Brazilian Doping Control Laboratory and Professor in the Department of Analytical Chemistry at the Federal University of Rio de Janeiro. Henrique is also President of the World Association of Anti-Doping Scientists (WAADS). In our conversation, we talk about his background, the Brazilian Doping Control Laboratory, and the role of WAADS in the anti-doping community. He also shares some of the important research that he and his colleagues are working on, including using a zebrafish water tank model to better understand the metabolism of prohibited substances and research aimed at better detecting use of cobalt, a prohibited substance that can impact red blood cell production.
120 – The State of the Science Surrounding Blood Collection Devices from Tasso, Inc. – Matthew Fedoruk, PhD
As a follow-up to our previous episode focused on innovative Blood Collection Devices from Tasso, Inc., Dr. Matthew Fedoruk joins us to discuss how Tasso’s blood collection devices are being used in anti-doping and the state of the science of what we can detect with these devices for anti-doping purposes. He covers important benefits of these devices, current limitations, and some of the key milestones and future directions for implementation in anti-doping testing. Dr. Fedoruk is Chief Science Officer at the U.S. Anti-Doping Agency (USADA), and he is also Co-Chair of the Partnership for Clean Competition’s Scientific Advisory Board.
119 – How Tasso is Innovating Blood Collection in Anti-Doping and Beyond – RJ Asplund and Erwin Berthier, PhD
Collecting blood samples is critical in anti-doping testing and a variety of clinical applications such as diagnostics and disease monitoring. However, traditional blood testing approaches can be a major pain point for athletes, sport organizations, patients, and their care teams. Tasso, Inc. is a company developing innovative products to improve the user experience surrounding blood collection. In this episode, Dr. Erwin Berthier and RJ Asplund describe Tasso’s current devices and how they work, the benefits of these products, and how their work is helping advance anti-doping. Erwin is Co-Founder and Chief Technology Officer and RJ is Vice President of Commercial at Tasso, Inc.
118 – Developing Novel Methods and Biomarkers to Detect Growth Hormone Doping – Martin Bidlingmaier, MD
Dr. Martin Bidlingmaier is Head of the Endocrine Laboratory, and he leads the Neuroendocrine Research Group in the Department of Internal Medicine at the Ludwig-Maximilians-University of Munich. Martin conducts clinical and basic research, particularly focusing on the development and validation of laboratory methods to diagnose and monitor pituitary and adrenal hormones, physiology, pathophysiology and biomarkers of growth hormone action, and endocrine aspects of doping in sports. In this episode, we discuss his work identifying new biomarkers and developing novel methods to measure growth hormone and detect growth hormone doping. He describes how growth hormone isoforms and the formation of complexes can help distinguish doping, and how the protein soluble α-klotho has emerged as a potential biomarker that may be useful in anti-doping analyses.
117 – Keeping Sport Clean in New Zealand and Beyond – Nick Paterson
Nick Paterson is Chief Executive of Drug Free Sport New Zealand, which will soon become part of a new Integrity Sport and Recreation Commission in New Zealand. He is also Governing Board Chair for the Institute of Anti-Doping Organisations (iNADO). In this episode, Nick talks more about Drug Free Sport New Zealand, including the organization’s history, the resources and services they provide, and their role in the global anti-doping community. He also discusses upcoming changes for sport integrity in New Zealand, and their key focus areas for the future.
116 – Reflecting on MLB’s Anti-Doping Efforts and the First 15 Years of the PCC – Jon Coyles and Dr. Gary Green
To wrap up our celebration this year of the 15th anniversary of the Partnership for Clean Competition, this episode features two guests from Major League Baseball (MLB), one of the PCC’s Founding Partner Organizations. Jon Coyles, JD, is Vice President of Drug, Health and Safety Programs, and Gary Green, MD, is Medical Director of MLB. In addition, Jon is a member of the PCC’s Board of Governors, and Gary is a Member of the PCC’s Scientific Advisory Board. In our interview, Jon and Gary share their perspectives on clean sport in baseball, the history of the PCC, important impacts the organization has had in anti-doping over the past fifteen years, collaborations between the PCC and MLB, and more.
115 – Supporting Anti-Doping Careers and Advancing Hematology Research – Mike Sawka, PhD
Dr. Mike Sawka is Chief Scientific Officer at Environmental Physiology and Hydration Associates, an Adjunct Professor at Georgia Tech, and a Member of the PCC’s Scientific Advisory Board and the Performance Hematology Working Group. He is also a Fellow of the American Physiological Society (APS). Today, we’re excited to talk about Mike’s career, his work with the PCC over the years, and his involvement with the American Physiological Society. He will also be discussing initiatives from the PCC and the APS designed to attract early-career and established researchers to the field of anti-doping, as well as some of the success stories to date.