The Partnership for Clean Competition aims to promote a holistic understanding of anti-doping. To move toward that goal, we’ve put together a selection of articles published in March 2021 that are relevant to clean sport. These articles may or may not stem from PCC-funded research. Posting them here should not be read as an endorsement of findings, but rather, an attempt to assemble the latest research in one place to make it easy to read and review.
Albertsdóttir AD, Van Gansbeke W, Van Eenoo P, Polet M. Enabling the inclusion of non-hydrolysed sulfated long term anabolic steroid metabolites in a screening for doping substances by means of gas chromatography quadrupole time-of-flight mass spectrometry. J Chromatogr A. 2021 Mar 5;16[42:46]2039. doi: 10.1016/j.chroma.2021.462039. Epub ahead of print. PMID: 33735641. https://pubmed.ncbi.nlm.nih.gov/33735641/
Alexander LA, Eken MM, Teoh CS, Stuart MC, Derman EW, Blauwet CA. PATTERNS OF ATHLETE MEDICATION USE AT THE 2018 PYEONGCHANG PARALYMPIC GAMES: A DESCRIPTIVE COHORT STUDY. Am J Phys Med Rehabil. 2021 Mar 16. doi: 10.1097/PHM.0000000000001751. Epub ahead of print. PMID: 33782274. https://pubmed.ncbi.nlm.nih.gov/33782274/
Astolfi T, Crettaz von Roten F, Kayser B, Saugy M, Faiss R. The Influence of Training Load on Hematological Athlete Biological Passport Variables in Elite Cyclists. Front Sports Act Living. 2021 Mar 18;[3:61]8285. doi: 10.3389/fspor.2021.618285. PMID: 33817634; PMCID: PMC8012815. https://pubmed.ncbi.nlm.nih.gov/33817634/
Jeppesen JS, Breenfeldt Andersen A, Bonne TC, Thomassen M, Sørensen H, Nordsborg NB, Olsen NV, Huertas JR, Bejder J. Immature reticulocytes are sensitive and specific to low-dose erythropoietin treatment at sea level and altitude. Drug Test Anal. 2021 Mar 19. doi: 10.1002/dta.3031. Epub ahead of print. PMID: 33739618. https://pubmed.ncbi.nlm.nih.gov/33739618/
Kraiem S, Al-Jaber MY, Al-Mohammed H, Al-Menhali AS, AlThani NJ, Helaleh M, Samsam W, Touil S, Beotra A, Georgakopoulas C, Bouabdallah S, Mohamed-Ali V, Almaadheed M. Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)-SCID mice with humanised liver, human urine samples and estimation of prevalence of its use in anti-doping samples. Drug Test Anal. 2021 Mar 23. doi: 10.1002/dta.3032. Epub ahead of print. PMID: 33759363. https://pubmed.ncbi.nlm.nih.gov/33759363/
Loke S, Liu L, Wenzel M, Scheffler H, Iannone M, de la Torre X, Schlörer N, Botrè F, Keiler AM, Bureik M, Parr MK. New Insights into the Metabolism of Methyltestosterone and Metandienone: Detection of Novel A-Ring Reduced Metabolites. Molecules. 2021 Mar 3;26(5):1354. doi: 10.3390/molecules26051354. PMID: 33802606. https://pubmed.ncbi.nlm.nih.gov/33802606/
Martinez Brito D, Leogrande P, Botrè F, de la Torre X. Detection of urinary arimistane metabolites in humans by liquid chromatography mass spectrometry. Complementary results to gas chromatography mass spectrometric data and its application to antidoping analyses. Rapid Commun Mass Spectrom. 2021 Mar 13:e9080. doi: 10.1002/rcm.9080. Epub ahead of print. PMID: 33713366. https://pubmed.ncbi.nlm.nih.gov/33713366/
Martínez Brito D, Leogrande P, Colamonici C, Curcio D, Botre F, de la Torre X. Arimistane: degradation product or metabolite of 7-oxo-DHEA? Drug Test Anal. 2021 Mar 30. doi: 10.1002/dta.3036. Epub ahead of print. PMID: 33783974. https://pubmed.ncbi.nlm.nih.gov/33783974/
Sakellariou P, Petrou M, Lyris E, Tsivou M, Fragkaki A, Kiousi P, Angelis YS, Pistos C. Determination of salmeterol, α-hydroxysalmeterol and fluticasone propionate in human urine and plasma for doping control using UHPLC-QTOF-MS. Biomed Chromatogr. 2021 Mar 15:e5114. doi: 10.1002/bmc.5114. Epub ahead of print. PMID: 33720401. https://pubmed.ncbi.nlm.nih.gov/33720401/
Solheim SA, Levernaes MCS, Mørkeberg J, Juul A, Upners EN, Nordsborg NB, Dehnes Y. Stability and detectability of testosterone esters in Dried Blood Spots after intramuscular injections. Drug Test Anal. 2021 Mar 17. doi: 10.1002/dta.3030. Epub ahead of print. PMID: 33733610. https://pubmed.ncbi.nlm.nih.gov/33733610/
Yuan Y, Xu Y, Lu J. Dried blood spots in doping analysis. Bioanalysis. 2021 Apr;13(7):587-604. doi: 10.4155/bio-2021-0019. Epub 2021 Mar 17. PMID: 33728984. https://pubmed.ncbi.nlm.nih.gov/33728984/
If you have ideas, questions, or potentially relevant research to include, please contact Communications Director David Kumbroch at dkumbroch@cleancompetition.org.
